Jonathan's grandson Joseph teams up with Will's grandson Caesar Zeppeli to battle ancient humanoids called the Pillar Men, but are overwhelmed by the Pillar Man Wamuu. The second part, Battle Tendency, takes place in 1939. However, Jonathan's wife Erina is pregnant with a child and escapes, continuing the Joestar name.

Speedwagon at his side, George's son Jonathan trains in Hamon and stops Dio who is left aboard an exploding ship after he mortally wounds Jonathan. Zeppeli, a master of a supernatural ability called Hamon, and former street thug Robert E.O. Dio's attempts to become the sole heir to the Joestar fortune are thwarted and he resorts to using an ancient Stone Mask which transforms him into a vampire with his sights now set on world domination. George Joestar takes in the orphan Dio Brando to pay off a debt to Dio's late father Dario. The first part, Phantom Blood, is set in the early-to-late 1880s in England. The first season was split into two parts: part 1 comprised episodes 1–9 covering the Phantom Blood manga arc, and part 2 comprised episodes 10–26 covering the Battle Tendency arc. A second season, JoJo's Bizarre Adventure: Stardust Crusaders, based on the series' third arc, began airing from April 5, 2014. Viz Media released an English Blu-ray set on Jthat includes English and Japanese audio with new subtitles for the Japanese. The English DVD was released by Warner Home Video on Septemwith both English and Japanese audio with closed captioning for the English dub only. Crunchyroll began streaming the series in April 2014.

The series was released on a series of nine DVDs and Blu-rays between January 30 and September 27, 2013, with the Blu-ray releases having the option of English subtitles. The Battle Tendency arc, which aired on Tokyo MX between December 8, 2012, and April 6, 2013, focuses on Jonathan's grandson, Joseph Joestar, and his fight against the Pillar Men, ancient humanoids which created the Stone Mask. The Phantom Blood arc, which aired on Tokyo MX between October 6 and December 1, 2012, revolves around the mysterious adventures of the Joestar family, beginning with an encounter involving Jonathan Joestar, his adoptive brother Dio Brando, and a Stone Mask that transforms people into vampires. The first season of the 2012 anime television series JoJo's Bizarre Adventure ( ジョジョの奇妙な冒険, JoJo no Kimyō na Bōken) by David Production, also known as JoJo's Bizarre Adventure: The Animation, adapted the first two arcs of Hirohiko Araki's manga of the same name: Phantom Blood ( ファントムブラッド, Fantomu Buraddo) and Battle Tendency ( 戦闘潮流, Sentō Chōryū).

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